Molecular markers in bladder cancer

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منابع مشابه

The Promise of Novel Molecular Markers in Bladder Cancer

Bladder cancer is the fourth most common malignancy in the US and is associated with the highest cost per patient. A high likelihood of recurrence, mandating stringent surveillance protocols, has made the development of urinary markers a focus of intense pursuit with the hope of decreasing the burden this disease places on patients and the healthcare system. To date, routine use of markers is n...

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Urinary markers in bladder cancer.

OBJECTIVES Many markers for the detection of bladder cancers have been tested. Almost all urinary markers reported are better than cytology with regard to sensitivity, but they score lower in specificity. The purpose of this review is to highlight the most important urinary biomarkers studied and reported recently. METHODS Literature on bladder cancer markers has been reviewed regularly in th...

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Molecular markers for diagnosis, staging, and prognosis of bladder cancer.

Conventional histopathologic evaluation of bladder cancer, encompassing tumor grade and stage, is inadequate to accurately predict the behavior of most bladder tumors. Intense research efforts are under way to identify and characterize various bladder cancers and their true biological potential more effectively. The need to predict which superficial tumors will recur or progress--and which inva...

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Urinary markers for bladder cancer

Bladder cancer has the fifth highest incidence of all malignancies in the United States, with a propensity to recur, requiring lifelong surveillance after diagnosis. Urinary markers of disease have been of extreme interest in this field in an effort to simplify surveillance schedules and improve early detection of tumors. Many markers have been described, but most remain investigational. Howeve...

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EDITORIAL Markers of Bladder Cancer

For the urologist who is treating a patient with a flat or papillary lesion of the bladder, the most important question is whether the lesion will invade and/or metastasize. Traditionally, the criteria used to make a prognosis have been the multiplicity, size, and grade of the tumor. However, since most initial tumors are single, small, and of low grade, these criteria have not been reliable. I...

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ژورنال

عنوان ژورنال: Current Opinion in Urology

سال: 2008

ISSN: 0963-0643

DOI: 10.1097/mou.0b013e3282f1c5c1